HitPredict

Interactor 1: TAB3 (Q8N5C8)
TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 (Mitogen-activated protein kinase kinase kinase 7-interacting protein 3) (NF-kappa-B-activating protein 1) (TAK1-binding protein 3) (TAB-3) (TGF-beta-activated kinase 1-binding protein 3)
Gene: TAB3

Interactor 2: TRAF6 (Q9Y4K3)
TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (Interleukin-1 signal transducer) (RING finger protein 85) (RING-type E3 ubiquitin transferase TRAF6)
Gene: TRAF6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.92 0.60 0.743

The method score is based on:

Property Details
Experiments 36098982, 36593296, 27497262, 14633987, 27009840, 15327770, 12496252
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0008270 - zinc ion binding
GO:0010008 - endosome membrane
GO:0038061 - non-canonical NF-kappaB signal transduction
and 1 others

more...
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 712
Hs

1 522
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Last updated: 15 Jul 2024