Interactor 1: CISD2 (Q8N5K1)
CDGSH iron-sulfur domain-containing protein 2 (Endoplasmic reticulum intermembrane small protein) (MitoNEET-related 1 protein) (Miner1) (Nutrient-deprivation autophagy factor-1) (NAF-1)
Gene: CISD2

Interactor 2: CISD1 (Q9NZ45)
CDGSH iron-sulfur domain-containing protein 1 (Cysteine transaminase CISD1) (EC 2.6.1.3) (MitoNEET)
Gene: CISD1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains zf-CDGSH~zf-CDGSH
Common GO terms GO:0005741 - mitochondrial outer membrane
GO:0010506 - regulation of autophagy
GO:0042803 - protein homodimerization activity
GO:0046872 - metal ion binding
GO:0051537 - 2 iron, 2 sulfur cluster binding
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 135
Hs

1 108
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024