HitPredict

Interactor 1: TTC9C (Q8N5M4)
Tetratricopeptide repeat protein 9C (TPR repeat protein 9C)
Gene: TTC9C

Interactor 2: SGT1 (Q9Y2Z0)
Protein SGT1 homolog (Protein 40-6-3) (Sgt1) (Suppressor of G2 allele of SKP1 homolog)
Gene: SUGT1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 171 Hs			1 365
+	Hs
		972614 FKBP4_HUMAN (2-170): 1.94e-35: 130: 23.67		SGT1_HUMAN (1-365): 2.37e-88: 272: 100.00
+	Hs
		118804 AIP_HUMAN (2-171): 2.95e-35: 127: 21.05		SGT1_HUMAN (1-365): 2.37e-88: 272: 100.00
+	Hs
		1035065 FKBP5_HUMAN (2-170): 3.75e-33: 123: 21.30		SGT1_HUMAN (1-365): 2.37e-88: 272: 100.00
+	Hs
		1053266 FKBP8_HUMAN (2-171): 1.63e-30: 115: 26.47		SGT1_HUMAN (1-365): 2.37e-88: 272: 100.00
+	Mm
		1141237 PPP5_MOUSE (2-163): 1.11e-30: 117: 14.82		SGT1_MOUSE (1-365): 2.63e-76: 240: 74.25
+	Hs
		73118 FKBP4_HUMAN (2-170): 1.94e-35: 130: 23.67		B4DYC6_HUMAN (57-365): 4.31e-64: 207: 86.41
+	Dm
		1368585 Q9VJD4_DROME (3-171): 2.24e-30: 114: 17.54		Q9VJD4_DROME (9-226): 1.38e-47: 165: 17.73
+	Ps
		1341481 TOC64_PEA (6-156): 3.2e-32: 122: 18.54		TOC64_PEA (8-127): 6.71e-39: 147: 21.67
+	Hs
		213621 SGTB_HUMAN (1-157): 7.14e-34: 122: 17.83		SGTA_HUMAN (6-171): 3.42e-40: 146: 20.96
+	Hs
		858619 FKBP5_HUMAN (2-170): 3.75e-33: 123: 21.30		PPP5_HUMAN (9-242): 1.39e-38: 145: 14.71
+	Mm
		1141207 PPP5_MOUSE (2-163): 1.11e-30: 117: 14.82		PPP5_MOUSE (9-202): 3.13e-39: 147: 16.58
+	Hs
		1034998 FKBP5_HUMAN (2-170): 3.75e-33: 123: 21.30		RPAP3_HUMAN (3-129): 5.92e-27: 114: 14.17
+	Hs
		1053193 FKBP8_HUMAN (2-171): 1.63e-30: 115: 26.47		RPAP3_HUMAN (3-129): 5.92e-27: 114: 14.17
+	Hs
		1028045 FKBP8_HUMAN (2-171): 1.63e-30: 115: 26.47		DNJC3_HUMAN (6-326): 2.67e-25: 108: 15.69
+	Hs
		174814 FKBP4_HUMAN (2-170): 1.94e-35: 130: 23.67		OGT1_HUMAN (48-303): 5e-18: 87.6: 9.51
+	Hs
		174855 FKBP5_HUMAN (2-170): 3.75e-33: 123: 21.30		OGT1_HUMAN (48-303): 5e-18: 87.6: 9.51
+	Hs
		174884 FKBP8_HUMAN (2-171): 1.63e-30: 115: 26.47		OGT1_HUMAN (48-303): 5e-18: 87.6: 9.51
+	Hs
		297056 FKBP5_HUMAN (2-170): 3.75e-33: 123: 21.30		TOM70_HUMAN (3-221): 1.5e-09: 61.4: 9.29
+	Hs
		1290144 SGTB_HUMAN (1-157): 7.14e-34: 122: 17.83		SGTB_HUMAN (91-296): 3.48e-10: 62.2: 12.14
+	Sc
		549755 PPID_YEAST (2-171): 1.03e-21: 91.8: 24.71		STI1_YEAST (2-145): 1.79e-14: 76.4: 23.61