Interactor 1: I22R1 (Q8N6P7)
Interleukin-22 receptor subunit alpha-1 (IL-22 receptor subunit alpha-1) (IL-22R-alpha-1) (IL-22RA1) (Cytokine receptor class-II member 9) (Cytokine receptor family 2 member 9) (CRF2-9) (ZcytoR11)
Gene: IL22RA1

Interactor 2: I22R2 (Q969J5)
Interleukin-22 receptor subunit alpha-2 (IL-22 receptor subunit alpha-2) (IL-22R-alpha-2) (IL-22RA2) (Cytokine receptor class-II member 10) (Cytokine receptor family 2 member 10) (CRF2-10) (Cytokine receptor family type 2, soluble 1) (CRF2-S1) (Interleukin-22-binding protein) (IL-22BP) (IL22BP) (ZcytoR16)
Gene: IL22RA2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 15120653
Identification Methods enzyme linked immunosorbent assay
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Interfer-bind~Tissue_fac, Tissue_fac~Tissue_fac
Common GO terms GO:0019221 - cytokine-mediated signaling pathway
GO:0042018 - interleukin-22 receptor activity
GO:0050728 - negative regulation of inflammatory response
Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 574
Hs

1 263
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024