Interactor 1: I22R1 (Q8N6P7)
Interleukin-22 receptor subunit alpha-1 (IL-22 receptor subunit alpha-1) (IL-22R-alpha-1) (IL-22RA1) (Cytokine receptor class-II member 9) (Cytokine receptor family 2 member 9) (CRF2-9) (ZcytoR11)
Gene: IL22RA1

Interactor 2: IL22 (Q9GZX6)
Interleukin-22 (IL-22) (Cytokine Zcyto18) (IL-10-related T-cell-derived-inducible factor) (IL-TIF)
Gene: IL22

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.967

The method score is based on:

Property Details
Experiments 10875937, 11035029, 18599299, 20462497, 15120653, 12513909, 18675809
Identification Methods affinity chromatography technology, pull down, surface plasmon resonance, x-ray crystallography, enzyme linked immunosorbent assay, molecular sieving
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains IL22~Tissue_fac
Common GO terms GO:0050728 - negative regulation of inflammatory response
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 574
Hs

1 179
+ Hs
+ Mm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024