HitPredict

Interactor 1: ARFG1 (Q8N6T3)
ADP-ribosylation factor GTPase-activating protein 1 (ARF GAP 1) (ADP-ribosylation factor 1 GTPase-activating protein) (ARF1 GAP) (ARF1-directed GTPase-activating protein)
Gene: ARFGAP1

Interactor 2: CD2AP (Q9Y5K6)
CD2-associated protein (Adapter protein CMS) (Cas ligand with multiple SH3 domains)
Gene: CD2AP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 406 Hs			1 639
+	Hs
		1356881 ASAP1_HUMAN (6-89): 2.45e-12: 70.9: 38.10		CD2AP_HUMAN (1-639): 9.29e-139: 420: 100.00
+	Hs
		195796 ASAP2_HUMAN (6-88): 3.03e-14: 76.6: 45.78		Q5JPT6_HUMAN (1-638): 3.71e-91: 297: 32.43
+	Hs
		195804 ASAP2_HUMAN (6-88): 3.03e-14: 76.6: 45.78		SH3K1_HUMAN (1-638): 3.71e-91: 297: 32.43
+	Hs
		1285221 ASAP1_HUMAN (6-89): 2.45e-12: 70.9: 38.10		SH3K1_HUMAN (1-638): 3.71e-91: 297: 32.43
+	Hs
		924582 ACAP1_HUMAN (9-384): 3.07e-62: 215: 12.93		GRB2_HUMAN (112-328): 1.9e-40: 148: 18.27
+	Hs
		557696 ACAP1_HUMAN (9-384): 3.07e-62: 215: 12.93		NCK1_HUMAN (113-378): 9.79e-21: 96.5: 14.24
+	Ce
		185219 O18181_CAEEL (4-403): 3.59e-69: 228: 16.35		Q9U2T9_CAEEL (27-492): 3.56e-11: 68.5: 13.89
+	Hs
		1078880 SMAP2_HUMAN (5-356): 1.14e-65: 217: 14.40		ITSN1_HUMAN (1-55): 3.97e-11: 68.8: 43.64
+	Hs
		195770 ASAP2_HUMAN (6-88): 3.03e-14: 76.6: 45.78		NCK2_HUMAN (2-361): 2.2e-59: 205: 16.17
+	Hs
		209187 ASAP1_HUMAN (6-89): 2.45e-12: 70.9: 38.10		NCK2_HUMAN (2-361): 2.2e-59: 205: 16.17
+	Dm
		112584 Q9VPU3_DROME (1-385): 7.45e-51: 180: 16.43		M9ND00_DROME (213-549): 1.1e-13: 76.9: 11.30
+	Dm
		1367920 Q9VPU3_DROME (1-385): 7.45e-51: 180: 16.43		Q9VIF7_DROME (213-549): 1.66e-12: 73: 11.30
+	Hs
		275240 ASAP1_HUMAN (6-89): 2.45e-12: 70.9: 38.10		GRAP2_HUMAN (2-329): 1.68e-45: 166: 12.83
+	Hs
		195791 ASAP2_HUMAN (6-88): 3.03e-14: 76.6: 45.78		GRB2_HUMAN (112-328): 1.9e-40: 148: 18.27
+	Hs
		924943 ASAP1_HUMAN (6-89): 2.45e-12: 70.9: 38.10		GRB2_HUMAN (112-328): 1.9e-40: 148: 18.27
+	Hs
		195783 ASAP2_HUMAN (6-88): 3.03e-14: 76.6: 45.78		NCK1_HUMAN (113-378): 9.79e-21: 96.5: 14.24
+	Hs
		557823 ASAP1_HUMAN (6-89): 2.45e-12: 70.9: 38.10		NCK1_HUMAN (113-378): 9.79e-21: 96.5: 14.24
+	Hs
		195795 ASAP2_HUMAN (6-88): 3.03e-14: 76.6: 45.78		ITSN1_HUMAN (1-55): 3.97e-11: 68.8: 43.64