HitPredict

Interactor 1: SIR6 (Q8N6T7)
NAD-dependent protein deacylase sirtuin-6 (EC 2.3.1.-) (NAD-dependent protein deacetylase sirtuin-6) (EC 2.3.1.286) (Protein mono-ADP-ribosyltransferase sirtuin-6) (EC 2.4.2.-) (Regulatory protein SIR2 homolog 6) (hSIRT6) (SIR2-like protein 6)
Gene: SIRT6

Interactor 2: Q96BE0 (Q96BE0)
Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8)
Gene: Q96BE0

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	25036637
Identification Methods	luminescence based mammalian interactome mapping
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 355 Hs			1 269
+	Hs
		714019 SIR6_HUMAN (1-355): 2.25e-166: 469: 100.00		HS71L_HUMAN (1-269): 2.79e-134: 395: 76.58
+	Hs
		504402 SIR6_HUMAN (1-355): 2.25e-166: 469: 100.00		HSP7C_HUMAN (1-269): 1.08e-130: 385: 100.00
+	Hs
		871671 SIR6_HUMAN (1-355): 2.25e-166: 469: 100.00		HSP72_HUMAN (1-269): 1.82e-126: 374: 78.07
+	Hs
		714048 SIR1_HUMAN (25-336): 3.35e-99: 311: 21.83		HS71L_HUMAN (1-269): 2.79e-134: 395: 76.58
+	Hs
		504364 SIR2_HUMAN (31-318): 3.2e-102: 308: 22.12		HSP7C_HUMAN (1-269): 1.08e-130: 385: 100.00
+	Hs
		871799 SIR7_HUMAN (22-321): 2.13e-101: 306: 38.61		HSP72_HUMAN (1-269): 1.82e-126: 374: 78.07
+	Hs
		714080 SIR3_HUMAN (33-287): 6.34e-90: 276: 27.92		HS71L_HUMAN (1-269): 2.79e-134: 395: 76.58