HitPredict

Interactor 1: EMC1 (Q8N766)
ER membrane protein complex subunit 1
Gene: EMC1

Interactor 2: EMC7 (Q9NPA0)
Endoplasmic reticulum membrane protein complex subunit 7 (ER membrane protein complex subunit 7)
Gene: EMC7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.86	0.90	0.884

Property	Details
Experiments	22119785, 27342126, 33961781, 35271311, 28514442
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	EMC1_C~EMC7_beta-sandw, EMC7_beta-sandw~PQQ_2
Common GO terms	GO:0005789 - endoplasmic reticulum membrane GO:0016020 - membrane GO:0045050 - protein insertion into ER membrane by stop-transfer membrane-anchor sequence GO:0071816 - tail-anchored membrane protein insertion into ER membrane GO:0072546 - EMC complex
Homologous interactions	0