HitPredict

Interactor 1: UBL4B (Q8N7F7)
Ubiquitin-like protein 4B
Gene: UBL4B

Interactor 2: TRAF4 (Q9BUZ4)
TNF receptor-associated factor 4 (EC 2.3.2.27) (Cysteine-rich domain associated with RING and Traf domains protein 1) (Metastatic lymph node gene 62 protein) (MLN 62) (RING finger protein 83)
Gene: TRAF4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.81	1.00	0.901

Property	Details
Experiments	25416956, 32296183, unassigned1304, 31515488
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	ubiquitin~zf-C3HC4
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 174 Hs			1 470
+	Hs
		509725 UBL4A_HUMAN (1-153): 6.1e-39: 131: 42.41		TRAF4_HUMAN (1-470): 5.03e-120: 361: 100.00
+	Hs
		475011 UBB_HUMAN (1-72): 6.02e-33: 118: 30.56		TRAF2_HUMAN (2-465): 4.35e-117: 354: 29.86
+	Hs
		924227 RS27A_HUMAN (1-141): 3.76e-46: 150: 21.68		TRAF6_HUMAN (3-464): 1.61e-84: 271: 24.79
+	Hs
		509753 UBL4A_HUMAN (1-153): 6.1e-39: 131: 42.41		TRAF6_HUMAN (3-464): 1.61e-84: 271: 24.79
+	Hs
		475253 UBB_HUMAN (1-72): 6.02e-33: 118: 30.56		TRAF6_HUMAN (3-464): 1.61e-84: 271: 24.79
+	Dm
		547968 RS27A_DROME (1-159): 1.3e-44: 146: 19.26		Q9W3I9_DROME (2-464): 1.97e-72: 238: 19.49
+	Hs
		475013 UBB_HUMAN (1-72): 6.02e-33: 118: 30.56		TRAF1_HUMAN (16-465): 6.07e-72: 235: 24.18
+	Hs
		301744 RS27A_HUMAN (1-141): 3.76e-46: 150: 21.68		TRI37_HUMAN (5-465): 5.48e-55: 199: 13.81
+	Mm
		924236 RS27A_MOUSE (1-141): 1.15e-45: 148: 20.98		RO52_MOUSE (4-266): 2.26e-45: 166: 13.86
+	Hs
		924180 RS27A_HUMAN (1-141): 3.76e-46: 150: 21.68		ZNF71_HUMAN (4-216): 4.29e-41: 154: 13.95
+	Mm
		476671 UBB_MOUSE (1-72): 4.63e-32: 118: 30.56		RO52_MOUSE (4-266): 2.26e-45: 166: 13.86
+	Mm
		924253 RL40_MOUSE (1-112): 3.5e-34: 118: 21.43		RO52_MOUSE (4-266): 2.26e-45: 166: 13.86
+	Dm
		1182271 PRKN_DROME (1-150): 1.45e-38: 138: 17.76		Q9VUV7_DROME (3-129): 1.22e-33: 130: 28.03
+	Hs
		475125 UBB_HUMAN (1-72): 6.02e-33: 118: 30.56		RN166_HUMAN (9-146): 3.64e-16: 79.5: 25.90
+	At
		1091851 UBQ3_ARATH (1-77): 1e-31: 117: 27.27		Q8W1E7_ARATH (80-231): 4.23e-12: 70.3: 22.88
+	Hs
		563294 RL40_HUMAN (1-112): 3.5e-34: 118: 21.43		ZNF16_HUMAN (215-353): 3.68e-10: 64.1: 6.48