Interactor 1: PAF1 (Q8N7H5)
RNA polymerase II-associated factor 1 homolog (hPAF1) (Pancreatic differentiation protein 2)
Gene: PAF1
Interactor 2: LEO1 (Q8WVC0)
RNA polymerase-associated protein LEO1 (Replicative senescence down-regulated leo1-like protein)
Gene: LEO1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.96 | 1.00 | 0.984 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25416956, 32296183, 33961781, 18469135, 20178742, 20305087, 21726809, 26496610, 24981860, 15632063, 35235311, 16024656, unassigned1304, 19410543 |
| Identification Methods | two hybrid, affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation, two hybrid prey pooling approach, two hybrid array, validated two hybrid, tandem affinity purification, anti bait coimmunoprecipitation |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Leo1~Paf1 |
| Common GO terms | GO:0001650 - fibrillar center GO:0001711 - endodermal cell fate commitment GO:0005654 - nucleoplasm GO:0006368 - transcription elongation by RNA polymerase II GO:0016055 - Wnt signaling pathway and 5 others more... |
| Homologous interactions | 9 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
