Interactor 1: CGAS (Q8N884)
Cyclic GMP-AMP synthase (cGAMP synthase) (cGAS) (h-cGAS) (EC 2.7.7.86) (2'3'-cGAMP synthase) (Mab-21 domain-containing protein 1)
Gene: CGAS

Interactor 2: RN185 (Q96GF1)
E3 ubiquitin-protein ligase RNF185 (EC 2.3.2.27) (RING finger protein 185)
Gene: RNF185

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.66 0.60 0.629

The method score is based on:

Property Details
Experiments 28273161, 36966392
Identification Methods affinity chromatography technology, enzymatic study
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0045087 - innate immune response
GO:0046872 - metal ion binding
GO:0051607 - defense response to virus
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 522
Hs

1 192
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024