HitPredict

Interactor 1: CGAS (Q8N884)
Cyclic GMP-AMP synthase (cGAMP synthase) (cGAS) (h-cGAS) (EC 2.7.7.86) (2'3'-cGAMP synthase) (Mab-21 domain-containing protein 1)
Gene: CGAS

Interactor 2: CHMP3 (Q9Y3E7)
Charged multivesicular body protein 3 (Chromatin-modifying protein 3) (Neuroendocrine differentiation factor) (Vacuolar protein sorting-associated protein 24) (hVps24)
Gene: CHMP3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30471916
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005546 - phosphatidylinositol-4,5-bisphosphate binding GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 522 Hs			1 222
+	Hs
		208848 CGAS_HUMAN (1-522): 0: 680: 100.00		CHM2A_HUMAN (7-221): 5.79e-45: 151: 24.19
+	Hs
		1237525 CGAS_HUMAN (1-522): 0: 680: 100.00		CHM2B_HUMAN (8-208): 4.24e-43: 146: 25.87
+	Hs
		1237482 CGAS_HUMAN (1-522): 0: 680: 100.00		CHM1A_HUMAN (22-222): 5.49e-36: 127: 13.43
+	Hs
		1237475 CGAS_HUMAN (1-522): 0: 680: 100.00		CHM4B_HUMAN (10-208): 2.44e-13: 68.2: 17.31
+	Hs
		1237442 CGAS_HUMAN (1-522): 0: 680: 100.00		CHM4C_HUMAN (10-215): 2.19e-10: 60.1: 14.82