HitPredict

Interactor 1: ANR44 (Q8N8A2)
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B (PP6-ARS-B) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-B) (Ankyrin repeat domain-containing protein 44)
Gene: ANKRD44

Interactor 2: PLK2 (Q9NYY3)
Serine/threonine-protein kinase PLK2 (EC 2.7.11.21) (Polo-like kinase 2) (PLK-2) (hPlk2) (Serine/threonine-protein kinase SNK) (hSNK) (Serum-inducible kinase)
Gene: PLK2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.80	0.770

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ank~Pkinase, Ank_2~Pkinase, Ank_4~Pkinase
Common GO terms	-
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 993 Hs			1 685
+	Hs
		861846 ANR52_HUMAN (1-674): 2.4e-119: 393: 24.42		PLK1_HUMAN (88-680): 0: 551: 37.98
+	Hs
		861724 ANK3_HUMAN (572-992): 6.43e-99: 345: 26.61		PLK1_HUMAN (88-680): 0: 551: 37.98
+	Hs
		167024 ANR28_HUMAN (1-148): 9.57e-21: 100: 23.24		PLK2_HUMAN (1-685): 0: 638: 100.00
+	Hs
		861845 ANR44_HUMAN (706-993): 1.09e-44: 177: 25.69		PLK1_HUMAN (88-680): 0: 551: 37.98
+	Hs
		166901 ANR28_HUMAN (1-148): 9.57e-21: 100: 23.24		PLK1_HUMAN (88-680): 0: 551: 37.98
+	Dm
		1362725 ANKHM_DROME (1-129): 9.77e-26: 117: 26.72		Q9VR61_DROME (47-338): 7.28e-95: 315: 28.11