HitPredict

Interactor 1: ENAH (Q8N8S7)
Protein enabled homolog
Gene: ENAH

Interactor 2: NECT4 (Q96NY8)
Nectin-4 (Ig superfamily receptor LNIR) (Nectin cell adhesion molecule 4) (Poliovirus receptor-related protein 4) [Cleaved into: Processed poliovirus receptor-related protein 4]
Gene: NECTIN4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 591 Hs			1 510
+	Hs
		1298943 EVL_HUMAN (1-374): 7.41e-27: 115: 32.71		NECT4_HUMAN (1-510): 1.12e-99: 311: 100.00
+	Ce
		103937 H2L0C7_CAEEL (14-177): 4.04e-41: 153: 26.90		SAX3_CAEEL (23-495): 1.39e-49: 185: 14.67
+	Mm
		530214 HOME1_MOUSE (1-285): 2.08e-35: 138: 16.62		NCAM1_MOUSE (25-441): 5.65e-42: 162: 13.49
+	Mm
		1206831 MINK1_MOUSE (113-575): 8.76e-40: 158: 16.21		PTK7_MOUSE (32-322): 1.28e-31: 131: 15.31
+	Mm
		1149041 HOME1_MOUSE (1-285): 2.08e-35: 138: 16.62		CNTN4_MOUSE (31-486): 1.73e-36: 146: 9.32
+	Hs
		793660 MYO10_HUMAN (182-480): 4.53e-25: 112: 14.15		DCC_HUMAN (29-498): 1.49e-42: 164: 15.05
+	Hs
		160144 HGS_HUMAN (90-385): 6.31e-28: 120: 22.22		LRIG1_HUMAN (23-458): 1.41e-25: 113: 13.51
+	Dm
		219807 ENA_DROME (2-491): 1.84e-26: 116: 23.88		O44924_DROME (245-510): 1.55e-21: 100: 13.70
+	Hs
		1264771 TITIN_HUMAN (81-495): 1.61e-25: 114: 11.06		TITIN_HUMAN (56-487): 3.66e-09: 61.7: 11.48