HitPredict

Interactor 1: LRC57 (Q8N9N7)
Leucine-rich repeat-containing protein 57
Gene: LRRC57

Interactor 2: SGT1 (Q9Y2Z0)
Protein SGT1 homolog (Protein 40-6-3) (Sgt1) (Suppressor of G2 allele of SKP1 homolog)
Gene: SUGT1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 239 Hs			1 365
+	Hs
		1294493 LRCH3_HUMAN (3-226): 6.07e-51: 178: 26.72		SGT1_HUMAN (1-365): 2.37e-88: 272: 100.00
+	Hs
		1050095 SCRIB_HUMAN (26-239): 1.16e-44: 161: 22.27		SGT1_HUMAN (1-365): 2.37e-88: 272: 100.00
+	Hs
		1312326 LRRC1_HUMAN (22-231): 4.67e-39: 143: 26.39		SGT1_HUMAN (1-365): 2.37e-88: 272: 100.00
+	Hs
		73168 LRCH3_HUMAN (3-226): 6.07e-51: 178: 26.72		B4DYC6_HUMAN (57-365): 4.31e-64: 207: 86.41
+	Hs
		1301469 ERBIN_HUMAN (2-148): 1.05e-26: 109: 27.21		SGT1_HUMAN (1-365): 2.37e-88: 272: 100.00
+	Hs
		1023260 FLII_HUMAN (107-238): 7.21e-21: 92.8: 19.15		SGT1_HUMAN (1-365): 2.37e-88: 272: 100.00
+	Hs
		1288119 LRC39_HUMAN (98-231): 1.24e-20: 90.5: 27.86		SGT1_HUMAN (1-365): 2.37e-88: 272: 100.00
+	Hs
		1377311 LRCH1_HUMAN (90-233): 2.44e-18: 85.5: 29.73		SGT1_HUMAN (1-365): 2.37e-88: 272: 100.00
+	Hs
		73173 LRRC1_HUMAN (22-231): 4.67e-39: 143: 26.39		B4DYC6_HUMAN (57-365): 4.31e-64: 207: 86.41
+	Hs
		264524 LRCH4_HUMAN (112-231): 1.5e-13: 71.3: 25.58		SGT1_HUMAN (1-365): 2.37e-88: 272: 100.00
+	Hs
		73166 LRC39_HUMAN (98-231): 1.24e-20: 90.5: 27.86		B4DYC6_HUMAN (57-365): 4.31e-64: 207: 86.41
+	Hs
		73195 LRCH1_HUMAN (90-233): 2.44e-18: 85.5: 29.73		B4DYC6_HUMAN (57-365): 4.31e-64: 207: 86.41
+	Hs
		858664 LRRC1_HUMAN (22-231): 4.67e-39: 143: 26.39		PPP5_HUMAN (9-242): 1.39e-38: 145: 14.71
+	Hs
		73175 LRRC2_HUMAN (18-211): 2.09e-16: 79: 31.63		B4DYC6_HUMAN (57-365): 4.31e-64: 207: 86.41
+	Hs
		174879 SCRIB_HUMAN (26-239): 1.16e-44: 161: 22.27		OGT1_HUMAN (48-303): 5e-18: 87.6: 9.51
+	Hs
		858616 FLII_HUMAN (107-238): 7.21e-21: 92.8: 19.15		PPP5_HUMAN (9-242): 1.39e-38: 145: 14.71
+	Dm
		1364726 SUR8_DROME (13-186): 1.71e-15: 77: 31.64		Q9VH81_DROME (4-218): 1.63e-39: 148: 13.58
+	Hs
		1138587 LRCH2_HUMAN (89-215): 2.86e-21: 94: 25.78		RPAP3_HUMAN (3-129): 5.92e-27: 114: 14.17
+	Hs
		1332494 PIDD1_HUMAN (6-161): 2.83e-15: 76.6: 33.33		RPAP3_HUMAN (3-129): 5.92e-27: 114: 14.17
+	Hs
		1332525 MFHA1_HUMAN (123-239): 4.97e-15: 75.8: 17.60		RPAP3_HUMAN (3-129): 5.92e-27: 114: 14.17