HitPredict

Interactor 1: TRIML (Q8N9V2)
Probable E3 ubiquitin-protein ligase TRIML1 (EC 2.3.2.27) (RING finger protein 209) (RING-type E3 ubiquitin transferase TRIML1) (Tripartite motif family-like protein 1)
Gene: TRIML1

Interactor 2: HOIL1 (Q9BYM8)
RanBP-type and C3HC4-type zinc finger-containing protein 1 (EC 2.3.2.31) (HBV-associated factor 4) (Heme-oxidized IRP2 ubiquitin ligase 1) (HOIL-1) (Hepatitis B virus X-associated protein 4) (RING finger protein 54) (RING-type E3 ubiquitin transferase HOIL-1) (Ubiquitin-conjugating enzyme 7-interacting protein 3)
Gene: RBCK1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	22493164
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0046872 - metal ion binding
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 468 Hs			1 510
+	Hs
		585055 RO52_HUMAN (1-465): 6.53e-156: 452: 36.81		HOIL1_HUMAN (1-510): 0: 577: 100.00
+	Hs
		312476 RO52_HUMAN (1-465): 6.53e-156: 452: 36.81		ARI2_HUMAN (243-496): 7.23e-65: 220: 19.85
+	Hs
		226489 RO52_HUMAN (1-465): 6.53e-156: 452: 36.81		PRKN_HUMAN (210-489): 2.2e-53: 188: 19.80
+	Hs
		312466 TRI27_HUMAN (1-466): 8.79e-142: 418: 29.64		ARI2_HUMAN (243-496): 7.23e-65: 220: 19.85
+	Hs
		226415 TRI27_HUMAN (1-466): 8.79e-142: 418: 29.64		PRKN_HUMAN (210-489): 2.2e-53: 188: 19.80
+	Hs
		228617 TRIM6_HUMAN (3-466): 8.52e-122: 366: 28.95		PRKN_HUMAN (210-489): 2.2e-53: 188: 19.80
+	Hs
		228594 TRI34_HUMAN (1-466): 3.71e-101: 312: 27.29		PRKN_HUMAN (210-489): 2.2e-53: 188: 19.80
+	Hs
		229073 TRI35_HUMAN (3-468): 9.73e-101: 312: 23.76		PRKN_HUMAN (210-489): 2.2e-53: 188: 19.80