HitPredict

Interactor 1: SPT5H (O00267)
Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor 160 kDa subunit) (DSIF p160) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (Tat-cotransactivator 1 protein) (Tat-CT1 protein)
Gene: SUPT5H

Interactor 2: PP4C (P60510)
Serine/threonine-protein phosphatase 4 catalytic subunit (PP4C) (Pp4) (EC 3.1.3.16) (Protein phosphatase X) (PP-X)
Gene: PPP4C

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.60	0.699

Property	Details
Experiments	27880917, 24981860, 29395067, 35271311
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 1087 Hs			1 307
+	Hs
		123902 SPT5H_HUMAN (1-1087): 0: 1061: 100.00		PP2AB_HUMAN (6-307): 0: 523: 65.23
+	Hs
		123911 SPT5H_HUMAN (1-1087): 0: 1061: 100.00		PP2AA_HUMAN (6-307): 0: 522: 65.89
+	Sc
		650246 SPT5_YEAST (5-944): 0: 594: 23.73		PP4C_YEAST (6-307): 7.03e-149: 421: 63.07
+	Hs
		90115 D6REX3_HUMAN (638-1072): 1.66e-30: 132: 11.23		PP1A_HUMAN (2-304): 0: 517: 43.89
+	Mm
		906254 SC31A_MOUSE (705-1072): 2.48e-27: 122: 11.88		PP1A_MOUSE (2-304): 0: 518: 44.20
+	Hs
		930947 LPP_HUMAN (612-895): 8.64e-10: 64.9: 9.79		PP2AA_HUMAN (6-307): 0: 522: 65.89
+	Hs
		302276 SC31A_HUMAN (795-1060): 7.42e-11: 68.8: 12.20		PP1A_HUMAN (2-304): 0: 517: 43.89
+	Mm
		906284 ZMIZ1_MOUSE (631-1000): 2.78e-10: 66.8: 15.37		PP1A_MOUSE (2-304): 0: 518: 44.20
+	Mm
		906278 ASPP1_MOUSE (646-1048): 3.62e-10: 66.4: 13.00		PP1A_MOUSE (2-304): 0: 518: 44.20
+	Hs
		906196 ZMIZ1_HUMAN (672-1039): 7.88e-10: 65.3: 10.22		PP1A_HUMAN (2-304): 0: 517: 43.89
+	Dm
		619884 Q8INT9_DROME (852-978): 8.39e-09: 60.2: 24.82		PP2A_DROME (2-307): 0: 522: 64.05
+	Hs
		737954 CBP_HUMAN (747-1035): 5.79e-09: 62.6: 12.81		PP1G_HUMAN (1-304): 0: 518: 43.81
+	Hs
		906058 CBP_HUMAN (747-1035): 5.79e-09: 62.6: 12.81		PP1A_HUMAN (2-304): 0: 517: 43.89