Interactor 1: A16L2 (Q8NAA4)
Protein Atg16l2 (APG16-like 2) (Autophagy-related protein 16-2) (WD repeat-containing protein 80)
Gene: ATG16L2

Interactor 2: ATG5 (Q9H1Y0)
Autophagy protein 5 (APG5-like) (Apoptosis-specific protein)
Gene: ATG5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.86 0.60 0.719

The method score is based on:

Property Details
Experiments 31636955, 22082872, 33961781, 21575909, 20562859
Identification Methods pull down, affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000045 - autophagosome assembly
GO:0005829 - cytosol
GO:0016236 - macroautophagy
GO:0034045 - phagophore assembly site membrane
GO:0034274 - Atg12-Atg5-Atg16 complex
and 1 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 619
Hs

1 275
+ Hs
+ Mm
+ Hs
+ Dm
+ Ce
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024