HitPredict

Interactor 1: PR38A (Q8NAV1)
Pre-mRNA-splicing factor 38A
Gene: PRPF38A

Interactor 2: SRPK1 (Q96SB4)
SRSF protein kinase 1 (EC 2.7.11.1) (SFRS protein kinase 1) (Serine/arginine-rich protein-specific kinase 1) (SR-protein-specific kinase 1)
Gene: SRPK1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.77	0.60	0.680

Property	Details
Experiments	22365833, 32707033, 23602568
Identification Methods	two hybrid, affinity chromatography technology, enzymatic study, pull down, protein kinase assay
Interaction Type	direct interaction, physical association, association, phosphorylation reaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 312 Hs			1 655
+	Hs
		942808 PR38A_HUMAN (1-312): 9.89e-159: 447: 100.00		SRPK2_HUMAN (48-655): 9.43e-136: 415: 57.97
+	Hs
		1239291 PR38A_HUMAN (1-312): 9.89e-159: 447: 100.00		SRPK3_HUMAN (29-654): 1.98e-99: 317: 38.95
+	Hs
		833927 PR38A_HUMAN (1-312): 9.89e-159: 447: 100.00		CLK2_HUMAN (484-653): 2.41e-63: 220: 29.07
+	Hs
		833774 PR38A_HUMAN (1-312): 9.89e-159: 447: 100.00		CLK1_HUMAN (436-654): 8.6e-61: 212: 23.45