HitPredict

Interactor 1: SPT5H (O00267)
Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor 160 kDa subunit) (DSIF p160) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (Tat-cotransactivator 1 protein) (Tat-CT1 protein)
Gene: SUPT5H

Interactor 2: MEP50 (Q9BQA1)
Methylosome protein WDR77 (Androgen receptor cofactor p44) (Methylosome protein 50) (MEP-50) (WD repeat-containing protein 77) (p44/Mep50)
Gene: WDR77

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	28977470, 24981860
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1087 Hs			1 342
+	Hs
		124074 SPT5H_HUMAN (1-1087): 0: 1061: 100.00		WDR33_HUMAN (58-331): 3.52e-67: 230: 17.86
+	Hs
		124015 SPT5H_HUMAN (1-1087): 0: 1061: 100.00		POC1A_HUMAN (201-341): 1.98e-27: 112: 18.31
+	Sc
		650278 SPT5_YEAST (5-944): 0: 594: 23.73		TAF5_YEAST (15-267): 2.96e-38: 146: 14.77
+	Hs
		1270779 CBP_HUMAN (747-1035): 5.79e-09: 62.6: 12.81		MEP50_HUMAN (1-342): 6.74e-81: 251: 100.00
+	Hs
		1274162 LPP_HUMAN (612-895): 8.64e-10: 64.9: 9.79		FBXW7_HUMAN (3-236): 5.23e-43: 159: 14.29
+	Hs
		302275 SC31A_HUMAN (795-1060): 7.42e-11: 68.8: 12.20		WDR5_HUMAN (247-341): 5.14e-19: 88.2: 19.79
+	Hs
		903374 KMT2C_HUMAN (634-1078): 3.48e-09: 63.4: 13.80		WDR5_HUMAN (247-341): 5.14e-19: 88.2: 19.79
+	Mm
		444958 RPB1_MOUSE (802-916): 3.3e-09: 63.3: 20.00		WDR5_MOUSE (247-341): 5.14e-19: 88.2: 19.79
+	Hs
		903405 CBP_HUMAN (747-1035): 5.79e-09: 62.6: 12.81		WDR5_HUMAN (247-341): 5.14e-19: 88.2: 19.79