HitPredict

Interactor 1: RN149 (Q8NC42)
E3 ubiquitin-protein ligase RNF149 (EC 2.3.2.27) (DNA polymerase-transactivated protein 2) (RING finger protein 149) (RING-type E3 ubiquitin transferase RNF149)
Gene: RNF149

Interactor 2: AMFR (Q9UKV5)
E3 ubiquitin-protein ligase AMFR (EC 2.3.2.36) (Autocrine motility factor receptor) (AMF receptor) (RING finger protein 45) (gp78)
Gene: AMFR

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 36610398
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains zf-RING_2~zf-RING_2
Common GO terms GO:0005783 - endoplasmic reticulum
GO:0005794 - Golgi apparatus
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0016020 - membrane
GO:0046872 - metal ion binding
and 1 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 400
Hs

1 643
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Zm
+ At
+ Hs
+ At
+ At
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024