HitPredict

Interactor 1: RETR2 (Q8NC44)
Reticulophagy regulator 2
Gene: RETREG2

Interactor 2: MLP3B (Q9GZQ8)
Microtubule-associated proteins 1A/1B light chain 3B (Autophagy-related protein LC3 B) (Autophagy-related ubiquitin-like modifier LC3 B) (MAP1 light chain 3-like protein 2) (MAP1A/MAP1B light chain 3 B) (MAP1A/MAP1B LC3 B) (Microtubule-associated protein 1 light chain 3 beta)
Gene: MAP1LC3B

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.50	0.548

Property	Details
Experiments	21900206, 26040720
Identification Methods	two hybrid, pull down
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 543 Hs			1 125
+	Hs
		1240862 RETR2_HUMAN (49-543): 0: 684: 100.00		MLP3A_HUMAN (1-120): 8.21e-55: 168: 82.50
+	Hs
		306234 RETR2_HUMAN (49-543): 0: 684: 100.00		GBRAP_HUMAN (7-121): 6.4e-53: 163: 31.30
+	Hs
		1240861 RETR2_HUMAN (49-543): 0: 684: 100.00		GBRL1_HUMAN (7-120): 1.5e-51: 160: 32.46
+	Hs
		1202374 RETR3_HUMAN (41-504): 0: 519: 33.83		MLP3B_HUMAN (1-125): 8.28e-57: 173: 100.00
+	Hs
		1202382 RETR3_HUMAN (41-504): 0: 519: 33.83		MLP3A_HUMAN (1-120): 8.21e-55: 168: 82.50
+	Hs
		891208 RETR3_HUMAN (41-504): 0: 519: 33.83		GBRL2_HUMAN (7-120): 2.21e-53: 165: 39.47
+	Hs
		306223 RETR3_HUMAN (41-504): 0: 519: 33.83		GBRAP_HUMAN (7-121): 6.4e-53: 163: 31.30
+	Hs
		1202377 RETR3_HUMAN (41-504): 0: 519: 33.83		GBRL1_HUMAN (7-120): 1.5e-51: 160: 32.46
+	Hs
		1326146 RETR1_HUMAN (57-509): 2.09e-175: 505: 28.98		MLP3B_HUMAN (1-125): 8.28e-57: 173: 100.00
+	Hs
		61903 RETR1_HUMAN (57-509): 2.09e-175: 505: 28.98		MP3B2_HUMAN (1-125): 5e-56: 172: 99.20
+	Hs
		1330625 RETR1_HUMAN (57-509): 2.09e-175: 505: 28.98		MLP3A_HUMAN (1-120): 8.21e-55: 168: 82.50
+	Hs
		891323 RETR1_HUMAN (57-509): 2.09e-175: 505: 28.98		GBRL2_HUMAN (7-120): 2.21e-53: 165: 39.47
+	Hs
		306320 RETR1_HUMAN (57-509): 2.09e-175: 505: 28.98		GBRAP_HUMAN (7-121): 6.4e-53: 163: 31.30
+	Mm
		1257559 RETR1_MOUSE (47-509): 2.61e-171: 495: 28.84		MLP3B_MOUSE (1-125): 1.09e-55: 171: 95.20
+	Hs
		1328030 RETR1_HUMAN (57-509): 2.09e-175: 505: 28.98		GBRL1_HUMAN (7-120): 1.5e-51: 160: 32.46