HitPredict

Interactor 1: SPT5H (O00267)
Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor 160 kDa subunit) (DSIF p160) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (Tat-cotransactivator 1 protein) (Tat-CT1 protein)
Gene: SUPT5H

Interactor 2: ZC3H4 (Q9UPT8)
Zinc finger CCCH domain-containing protein 4
Gene: ZC3H4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	29395067, 35271311
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0032785 - negative regulation of DNA-templated transcription, elongation
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1087 Hs			1 1303
+	Hs
		123781 SPT5H_HUMAN (1-1087): 0: 1061: 100.00		KMT2D_HUMAN (449-1287): 6.6e-11: 69.6: 10.38
+	Hs
		554259 MUC1_HUMAN (746-971): 1.34e-11: 71: 16.30		MUC1_HUMAN (728-1300): 1.93e-29: 129: 14.58
+	Hs
		1056910 CBP_HUMAN (747-1035): 5.79e-09: 62.6: 12.81		MDC1_HUMAN (467-1288): 1.36e-31: 137: 10.98
+	Dm
		113976 M9PB30_DROME (623-1074): 3.87e-11: 69.9: 10.12		M9PB30_DROME (399-1301): 3.33e-21: 103: 8.14
+	Hs
		317847 CBP_HUMAN (747-1035): 5.79e-09: 62.6: 12.81		CPSF4_HUMAN (356-540): 6.37e-20: 93.1: 17.45
+	Dm
		375663 RPB1_DROME (765-1072): 8.42e-11: 68.8: 12.35		Q9VLS7_DROME (504-1273): 5.44e-15: 82.8: 14.71
+	Hs
		1170076 CBP_HUMAN (747-1035): 5.79e-09: 62.6: 12.81		SRCAP_HUMAN (465-985): 1.37e-14: 81.5: 10.44
+	Hs
		152667 KMT2C_HUMAN (634-1078): 3.48e-09: 63.4: 13.80		KMT2D_HUMAN (449-1287): 6.6e-11: 69.6: 10.38
+	Hs
		152675 CBP_HUMAN (747-1035): 5.79e-09: 62.6: 12.81		KMT2D_HUMAN (449-1287): 6.6e-11: 69.6: 10.38
+	Mm
		1351630 PCLO_MOUSE (622-1063): 7.05e-09: 62.6: 11.82		PCLO_MOUSE (509-1299): 1.06e-09: 65.7: 8.41