HitPredict

Interactor 1: SEN2 (Q8NCE0)
tRNA-splicing endonuclease subunit Sen2 (EC 4.6.1.16) (tRNA-intron endonuclease Sen2) (HsSen2)
Gene: TSEN2

Interactor 2: SEN34 (Q9BSV6)
tRNA-splicing endonuclease subunit Sen34 (EC 4.6.1.16) (Leukocyte receptor cluster member 5) (tRNA-intron endonuclease Sen34) (HsSen34)
Gene: TSEN34

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.74 1.00 0.861

The method score is based on:

Property Details
Experiments 15109492, 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains tRNA_int_endo~tRNA_int_endo, tRNA_int_endo~tRNA_int_endo_N
Common GO terms GO:0000213 - tRNA-intron endonuclease activity
GO:0000214 - tRNA-intron endonuclease complex
GO:0000379 - tRNA-type intron splice site recognition and cleavage
GO:0003676 - nucleic acid binding
GO:0005654 - nucleoplasm
and 3 others

more...
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 465
Hs

1 310
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024