HitPredict

Interactor 1: DYHC2 (Q8NCM8)
Cytoplasmic dynein 2 heavy chain 1 (Cytoplasmic dynein 2 heavy chain) (Dynein cytoplasmic heavy chain 2) (Dynein heavy chain 11) (hDHC11) (Dynein heavy chain isotype 1B)
Gene: DYNC2H1

Interactor 2: DC2L1 (Q8TCX1)
Cytoplasmic dynein 2 light intermediate chain 1 (Dynein 2 light intermediate chain)
Gene: DYNC2LI1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.89	1.00	0.948

The method score is based on:

Property	Details
Experiments	12432068, 28514442, 11907264, 33961781, 35271311, 31451806
Identification Methods	affinity chromatography technology, molecular sieving, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	DHC_N1~DLIC
Common GO terms	GO:0005794 - Golgi apparatus GO:0005868 - cytoplasmic dynein complex GO:0005874 - microtubule GO:0005929 - cilium GO:0005930 - axoneme and 4 others more... GO:0007368 - determination of left/right symmetry GO:0035721 - intraciliary retrograde transport GO:0045177 - apical part of cell GO:0097542 - ciliary tip
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1	4307
Hs

1	351

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024