HitPredict

Interactor 1: TAF4 (O00268)
Transcription initiation factor TFIID subunit 4 (RNA polymerase II TBP-associated factor subunit C) (TBP-associated factor 4) (Transcription initiation factor TFIID 130 kDa subunit) (TAF(II)130) (TAFII-130) (TAFII130) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135)
Gene: TAF4

Interactor 2: ETV3 (P41162)
ETS translocation variant 3 (ETS domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor)
Gene: ETV3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1085 Hs			1 512
+	Hs
		124170 TAF4_HUMAN (1-1085): 1.72e-83: 296: 100.00		ELF1_HUMAN (4-403): 7.81e-53: 190: 19.74
+	Hs
		124252 TAF4_HUMAN (1-1085): 1.72e-83: 296: 100.00		ELF4_HUMAN (11-484): 1.89e-52: 190: 17.98
+	Hs
		124251 TAF4_HUMAN (1-1085): 1.72e-83: 296: 100.00		FEV_HUMAN (15-225): 9.09e-47: 164: 32.24
+	Hs
		124176 TAF4_HUMAN (1-1085): 1.72e-83: 296: 100.00		ELK3_HUMAN (49-430): 5.48e-38: 145: 17.05
+	Hs
		1077562 SRCAP_HUMAN (75-749): 9.61e-10: 65.4: 17.69		ELF2_HUMAN (9-452): 4.42e-70: 236: 19.29
+	Hs
		1243834 KMT2C_HUMAN (4-867): 7.32e-31: 134: 12.05		FEV_HUMAN (15-225): 9.09e-47: 164: 32.24
+	Hs
		507468 KMT2C_HUMAN (4-867): 7.32e-31: 134: 12.05		ERG_HUMAN (9-217): 1.57e-42: 159: 31.43
+	Hs
		840392 CRBG2_HUMAN (51-518): 6.53e-09: 62.3: 17.64		ERF_HUMAN (10-483): 4.79e-66: 224: 42.36
+	Hs
		1243851 KMT2C_HUMAN (4-867): 7.32e-31: 134: 12.05		ELF5_HUMAN (26-118): 5.7e-36: 136: 38.30
+	Hs
		1170079 SRCAP_HUMAN (75-749): 9.61e-10: 65.4: 17.69		ELF4_HUMAN (11-484): 1.89e-52: 190: 17.98
+	Hs
		692153 SRCAP_HUMAN (75-749): 9.61e-10: 65.4: 17.69		ELF1_HUMAN (4-403): 7.81e-53: 190: 19.74
+	Hs
		152681 KMT2D_HUMAN (37-835): 6.99e-09: 62.7: 9.11		ELF4_HUMAN (11-484): 1.89e-52: 190: 17.98
+	Hs
		542029 SRCAP_HUMAN (75-749): 9.61e-10: 65.4: 17.69		ETS1_HUMAN (18-140): 9.83e-50: 178: 44.72
+	Hs
		152583 KMT2D_HUMAN (37-835): 6.99e-09: 62.7: 9.11		ETS1_HUMAN (18-140): 9.83e-50: 178: 44.72
+	Hs
		152604 KMT2D_HUMAN (37-835): 6.99e-09: 62.7: 9.11		ETV5_HUMAN (5-149): 7.03e-44: 164: 33.79
+	Hs
		152680 KMT2D_HUMAN (37-835): 6.99e-09: 62.7: 9.11		FEV_HUMAN (15-225): 9.09e-47: 164: 32.24
+	Hs
		152581 KMT2D_HUMAN (37-835): 6.99e-09: 62.7: 9.11		ERG_HUMAN (9-217): 1.57e-42: 159: 31.43
+	Hs
		152607 KMT2D_HUMAN (37-835): 6.99e-09: 62.7: 9.11		ETV4_HUMAN (5-172): 5.2e-39: 150: 32.56
+	Hs
		152699 KMT2D_HUMAN (37-835): 6.99e-09: 62.7: 9.11		ELF5_HUMAN (26-118): 5.7e-36: 136: 38.30
+	Dm
		113976 M9PB30_DROME (75-891): 1.88e-18: 94.2: 8.57		M9PB30_DROME (124-485): 9.43e-09: 60.5: 10.87