HitPredict

Interactor 1: PRP8 (Q6P2Q9)
Pre-mRNA-processing-splicing factor 8 (220 kDa U5 snRNP-specific protein) (PRP8 homolog) (Splicing factor Prp8) (p220)
Gene: PRPF8

Interactor 2: TLS1 (Q9NZ63)
Splicing factor C9orf78 (Hepatocellular carcinoma-associated antigen 59)
Gene: C9orf78

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.78 0.55 0.657

The method score is based on:

Property Details
Experiments 28515276, 26472760, 35271311, 35241646
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000398 - mRNA splicing, via spliceosome
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0030623 - U5 snRNA binding
Homologous interactions 0

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Last updated: 11Aug2025