HitPredict

Interactor 1: TAF4 (O00268)
Transcription initiation factor TFIID subunit 4 (RNA polymerase II TBP-associated factor subunit C) (TBP-associated factor 4) (Transcription initiation factor TFIID 130 kDa subunit) (TAF(II)130) (TAFII-130) (TAFII130) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135)
Gene: TAF4

Interactor 2: H2B1D (P58876)
Histone H2B type 1-D (H2B-clustered histone 5) (HIRA-interacting protein 2) (Histone H2B.1 B) (Histone H2B.b) (H2B/b)
Gene: H2BC5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34349018
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0046982 - protein heterodimerization activity
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 1085 Hs			1 126
+	Hs
		124245 TAF4_HUMAN (1-1085): 1.72e-83: 296: 100.00		H2B1H_HUMAN (1-126): 8.88e-54: 166: 98.41
+	Hs
		241562 ANR11_HUMAN (28-979): 9.58e-37: 153: 12.29		H2B1K_HUMAN (1-126): 2.11e-53: 165: 98.41
+	Hs
		918458 ANR11_HUMAN (28-979): 9.58e-37: 153: 12.29		H2B1C_HUMAN (1-126): 1.71e-53: 165: 99.21
+	Hs
		707690 KMT2C_HUMAN (4-867): 7.32e-31: 134: 12.05		H2B1B_HUMAN (1-126): 1.77e-53: 165: 97.62
+	Hs
		918533 KMT2C_HUMAN (4-867): 7.32e-31: 134: 12.05		H2B1C_HUMAN (1-126): 1.71e-53: 165: 99.21
+	Hs
		1056847 MDC1_HUMAN (4-966): 1.09e-29: 130: 11.32		H2B2E_HUMAN (1-126): 9.91e-54: 166: 98.41
+	Hs
		1056919 MDC1_HUMAN (4-966): 1.09e-29: 130: 11.32		H2B1H_HUMAN (1-126): 8.88e-54: 166: 98.41
+	Hs
		707631 MDC1_HUMAN (4-966): 1.09e-29: 130: 11.32		H2B1B_HUMAN (1-126): 1.77e-53: 165: 97.62
+	Hs
		918364 MDC1_HUMAN (4-966): 1.09e-29: 130: 11.32		H2B1C_HUMAN (1-126): 1.71e-53: 165: 99.21
+	Hs
		1087182 OBSCN_HUMAN (66-532): 7.53e-16: 85.4: 19.48		H2B2E_HUMAN (1-126): 9.91e-54: 166: 98.41
+	Hs
		1087210 SRCAP_HUMAN (75-749): 9.61e-10: 65.4: 17.69		H2B2E_HUMAN (1-126): 9.91e-54: 166: 98.41
+	Hs
		707663 SRCAP_HUMAN (75-749): 9.61e-10: 65.4: 17.69		H2B1B_HUMAN (1-126): 1.77e-53: 165: 97.62
+	Hs
		918462 SRCAP_HUMAN (75-749): 9.61e-10: 65.4: 17.69		H2B1C_HUMAN (1-126): 1.71e-53: 165: 99.21
+	Hs
		152598 KMT2D_HUMAN (37-835): 6.99e-09: 62.7: 9.11		H2B1B_HUMAN (1-126): 1.77e-53: 165: 97.62
+	Hs
		1170067 SRCAP_HUMAN (75-749): 9.61e-10: 65.4: 17.69		H2B3B_HUMAN (1-126): 2.67e-51: 160: 95.24
+	Hs
		1170078 SRCAP_HUMAN (75-749): 9.61e-10: 65.4: 17.69		H2B1A_HUMAN (1-126): 5.53e-46: 146: 85.04