HitPredict

Interactor 1: TAF4 (O00268)
Transcription initiation factor TFIID subunit 4 (RNA polymerase II TBP-associated factor subunit C) (TBP-associated factor 4) (Transcription initiation factor TFIID 130 kDa subunit) (TAF(II)130) (TAFII-130) (TAFII130) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135)
Gene: TAF4

Interactor 2: ROCK1 (Q13464)
Rho-associated protein kinase 1 (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-35) (Rho-associated, coiled-coil-containing protein kinase 1) (Rho-associated, coiled-coil-containing protein kinase I) (ROCK-I) (p160 ROCK-1) (p160ROCK)
Gene: ROCK1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24981860
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1085 Hs			1 1354
+	Dm
		1370328 Q9VLS7_DROME (1-777): 1.05e-12: 75: 8.49		Q9VXE3_DROME (9-1347): 0: 615: 42.66
+	Hs
		148818 MDC1_HUMAN (4-966): 1.09e-29: 130: 11.32		CTRO_HUMAN (13-1292): 1.39e-130: 447: 20.62
+	Hs
		149481 PCLO_HUMAN (204-906): 1.22e-18: 94.6: 11.99		CTRO_HUMAN (13-1292): 1.39e-130: 447: 20.62
+	Dm
		973540 CPN_DROME (1-669): 1.24e-17: 90.4: 12.67		Q9VTY8_DROME (25-1170): 8.21e-128: 437: 22.30
+	Dm
		116377 CPN_DROME (1-669): 1.24e-17: 90.4: 12.67		M9PI41_DROME (25-1170): 5.41e-126: 432: 22.22
+	Dm
		1370292 Q9VLS7_DROME (1-777): 1.05e-12: 75: 8.49		Q9VTY8_DROME (25-1170): 8.21e-128: 437: 22.30
+	Hs
		1057021 MDC1_HUMAN (4-966): 1.09e-29: 130: 11.32		KS6A6_HUMAN (74-342): 2.11e-75: 268: 29.86