HitPredict

Interactor 1: TAF4 (O00268)
Transcription initiation factor TFIID subunit 4 (RNA polymerase II TBP-associated factor subunit C) (TBP-associated factor 4) (Transcription initiation factor TFIID 130 kDa subunit) (TAF(II)130) (TAFII-130) (TAFII130) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135)
Gene: TAF4

Interactor 2: H31T (Q16695)
Histone H3.1t (H3/t) (H3t) (H3/g) (Histone H3.4)
Gene: H3-4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.563

Property	Details
Experiments	20850016, 17884155
Identification Methods	unspecified method, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0046982 - protein heterodimerization activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1085 Hs			1 136
+	Hs
		124197 TAF4_HUMAN (1-1085): 1.72e-83: 296: 100.00		H31_HUMAN (1-136): 6.88e-62: 187: 97.06
+	Hs
		124198 TAF4_HUMAN (1-1085): 1.72e-83: 296: 100.00		H33_HUMAN (1-136): 4.53e-61: 185: 93.38
+	Hs
		1086248 TAF4B_HUMAN (205-1085): 1.3e-53: 204: 26.30		H31T_HUMAN (1-136): 2.65e-61: 186: 100.00
+	Hs
		935004 KMT2C_HUMAN (4-867): 7.32e-31: 134: 12.05		H31_HUMAN (1-136): 6.88e-62: 187: 97.06
+	Hs
		1086228 KMT2C_HUMAN (4-867): 7.32e-31: 134: 12.05		H31T_HUMAN (1-136): 2.65e-61: 186: 100.00
+	Hs
		952479 KMT2C_HUMAN (4-867): 7.32e-31: 134: 12.05		H33_HUMAN (1-136): 4.53e-61: 185: 93.38
+	Hs
		1174600 KMT2C_HUMAN (4-867): 7.32e-31: 134: 12.05		H32_HUMAN (1-136): 1.34e-60: 184: 96.32
+	Hs
		934763 MDC1_HUMAN (4-966): 1.09e-29: 130: 11.32		H31_HUMAN (1-136): 6.88e-62: 187: 97.06
+	Hs
		952338 MDC1_HUMAN (4-966): 1.09e-29: 130: 11.32		H33_HUMAN (1-136): 4.53e-61: 185: 93.38
+	Hs
		828275 ANR11_HUMAN (28-979): 9.58e-37: 153: 12.29		CENPA_HUMAN (9-133): 3.54e-44: 142: 49.24
+	Hs
		935440 CABIN_HUMAN (51-436): 7.14e-16: 85.4: 17.12		H31_HUMAN (1-136): 6.88e-62: 187: 97.06
+	Hs
		952733 CABIN_HUMAN (51-436): 7.14e-16: 85.4: 17.12		H33_HUMAN (1-136): 4.53e-61: 185: 93.38
+	Mm
		101827 F8WI37_MOUSE (212-886): 3e-13: 76.9: 9.62		H33_MOUSE (1-136): 4.53e-61: 185: 93.38
+	Hs
		934880 ADNP2_HUMAN (21-497): 1.22e-12: 74.7: 16.67		H31_HUMAN (1-136): 6.88e-62: 187: 97.06
+	Hs
		952405 ADNP2_HUMAN (21-497): 1.22e-12: 74.7: 16.67		H33_HUMAN (1-136): 4.53e-61: 185: 93.38
+	Hs
		934908 SRCAP_HUMAN (75-749): 9.61e-10: 65.4: 17.69		H31_HUMAN (1-136): 6.88e-62: 187: 97.06
+	Hs
		952426 SRCAP_HUMAN (75-749): 9.61e-10: 65.4: 17.69		H33_HUMAN (1-136): 4.53e-61: 185: 93.38
+	Hs
		152625 KMT2D_HUMAN (37-835): 6.99e-09: 62.7: 9.11		H31_HUMAN (1-136): 6.88e-62: 187: 97.06
+	Hs
		152661 KMT2D_HUMAN (37-835): 6.99e-09: 62.7: 9.11		H32_HUMAN (1-136): 1.34e-60: 184: 96.32
+	Sc
		730797 SEC31_YEAST (201-673): 1.92e-11: 70.8: 17.07		CENPA_YEAST (18-134): 1.65e-41: 139: 53.33