HitPredict

Interactor 1: MZT2A (Q6P582)
Mitotic-spindle organizing protein 2A (Mitotic-spindle organizing protein associated with a ring of gamma-tubulin 2A)
Gene: MZT2A

Interactor 2: GCP4 (Q9UGJ1)
Gamma-tubulin complex component 4 (GCP-4) (hGCP4) (Gamma-ring complex protein 76 kDa) (h76p) (hGrip76)
Gene: TUBGCP4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000931 - gamma-tubulin ring complex GO:0005813 - centrosome GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 158 Hs			1 667
+	Hs
		1239834 MZT2B_HUMAN (1-158): 3.4e-81: 238: 96.20		GCP4_HUMAN (1-667): 0: 663: 100.00
+	Hs
		1242569 MZT2A_HUMAN (1-158): 4.38e-83: 243: 100.00		GCP3_HUMAN (1-662): 2.31e-169: 509: 16.78
+	Hs
		1242575 MZT2A_HUMAN (1-158): 4.38e-83: 243: 100.00		GCP2_HUMAN (1-664): 2.75e-169: 508: 18.06
+	Hs
		1239814 MZT2B_HUMAN (1-158): 3.4e-81: 238: 96.20		GCP3_HUMAN (1-662): 2.31e-169: 509: 16.78
+	Hs
		1239821 MZT2B_HUMAN (1-158): 3.4e-81: 238: 96.20		GCP2_HUMAN (1-664): 2.75e-169: 508: 18.06
+	Hs
		1242571 MZT2A_HUMAN (1-158): 4.38e-83: 243: 100.00		GCP5_HUMAN (1-649): 1.21e-132: 417: 15.64
+	Hs
		1239818 MZT2B_HUMAN (1-158): 3.4e-81: 238: 96.20		GCP5_HUMAN (1-649): 1.21e-132: 417: 15.64
+	Hs
		1239822 MZT2B_HUMAN (1-158): 3.4e-81: 238: 96.20		Q9BVR6_HUMAN (137-474): 1.55e-103: 320: 100.00
+	Hs
		74221 MZT2B_HUMAN (1-158): 3.4e-81: 238: 96.20		B2RWN4_HUMAN (1-445): 4.22e-75: 265: 13.49
+	Hs
		1239817 MZT2B_HUMAN (1-158): 3.4e-81: 238: 96.20		GCP6_HUMAN (1-408): 7.44e-75: 264: 13.26