HitPredict

Interactor 1: TNR6A (Q8NDV7)
Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (EMSY interactor protein) (GW182 autoantigen) (Protein GW1) (Glycine-tryptophan protein of 182 kDa)
Gene: TNRC6A

Interactor 2: MED12 (Q93074)
Mediator of RNA polymerase II transcription subunit 12 (Activator-recruited cofactor 240 kDa component) (ARC240) (CAG repeat protein 45) (Mediator complex subunit 12) (OPA-containing protein) (Thyroid hormone receptor-associated protein complex 230 kDa component) (Trap230) (Trinucleotide repeat-containing gene 11 protein)
Gene: MED12

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	28813667
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0007492 - endoderm development
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 1962 Hs			1 2177
+	Hs
		1242603 TNR6A_HUMAN (1-1962): 0: 896: 100.00		KMT2C_HUMAN (1619-2174): 8.59e-16: 86.5: 10.80
+	Hs
		1057772 TNR6A_HUMAN (1-1962): 0: 896: 100.00		NCOA6_HUMAN (1716-2173): 1.71e-09: 65.7: 11.91
+	Hs
		1305722 TNR6B_HUMAN (44-1944): 3.32e-153: 521: 33.57		ATX2_HUMAN (1645-2176): 2.64e-11: 71.5: 9.32
+	Mm
		1207212 KMT2C_MOUSE (978-1884): 1.32e-29: 132: 11.29		NCOA6_MOUSE (1782-2166): 9.03e-10: 66.5: 13.89
+	Mm
		99853 F8WI37_MOUSE (978-1884): 1.38e-29: 131: 11.29		F6M2J9_MOUSE (1841-2175): 8.77e-09: 63: 13.27
+	Hs
		1270755 CBP_HUMAN (735-1745): 8.61e-21: 102: 9.54		CBP_HUMAN (1582-2176): 2.69e-11: 71.5: 13.45
+	Hs
		1057781 CBP_HUMAN (735-1745): 8.61e-21: 102: 9.54		NCOA6_HUMAN (1716-2173): 1.71e-09: 65.7: 11.91
+	Mm
		70879 F8VPR5_MOUSE (735-1757): 5.22e-19: 96.7: 10.60		EP300_MOUSE (1845-2169): 2.28e-10: 68.7: 22.10
+	Hs
		1170076 SRCAP_HUMAN (1139-1823): 1.12e-12: 75.9: 10.82		CBP_HUMAN (1582-2176): 2.69e-11: 71.5: 13.45
+	Hs
		1057773 KMT2C_HUMAN (1071-1765): 1.31e-13: 79.4: 10.54		NCOA6_HUMAN (1716-2173): 1.71e-09: 65.7: 11.91
+	Hs
		998940 EP300_HUMAN (789-1765): 6.73e-09: 63.6: 9.05		CBP_HUMAN (1582-2176): 2.69e-11: 71.5: 13.45
+	Mm
		1351630 PCLO_MOUSE (19-1290): 1.41e-09: 66: 10.73		PCLO_MOUSE (1546-2153): 1.3e-09: 66.1: 10.38
+	Dm
		113976 M9PB30_DROME (58-812): 9.58e-09: 63.2: 8.52		M9PB30_DROME (1590-2174): 5.73e-10: 67.3: 7.06
+	Hs
		998981 EP300_HUMAN (789-1765): 6.73e-09: 63.6: 9.05		ZN469_HUMAN (1786-2166): 9.37e-10: 66.5: 10.12
+	Hs
		998713 EP300_HUMAN (789-1765): 6.73e-09: 63.6: 9.05		NCOA6_HUMAN (1716-2173): 1.71e-09: 65.7: 11.91