HitPredict

Interactor 1: TNR6A (Q8NDV7)
Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (EMSY interactor protein) (GW182 autoantigen) (Protein GW1) (Glycine-tryptophan protein of 182 kDa)
Gene: TNRC6A

Interactor 2: CNO6L (Q96LI5)
CCR4-NOT transcription complex subunit 6-like (EC 3.1.13.4) (Carbon catabolite repressor protein 4 homolog B)
Gene: CNOT6L

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.670

Property	Details
Experiments	29395067, 21984185, 21981923
Identification Methods	proximity labelling technology, pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1962 Hs			1 555
+	Hs
		1242694 TNR6A_HUMAN (1-1962): 0: 896: 100.00		CNOT6_HUMAN (6-555): 4.41e-108: 336: 77.38
+	Hs
		1297142 TNR6B_HUMAN (44-1944): 3.32e-153: 521: 33.57		CNO6L_HUMAN (1-555): 3.57e-109: 338: 100.00
+	Hs
		1356954 TNR6B_HUMAN (44-1944): 3.32e-153: 521: 33.57		CNOT6_HUMAN (6-555): 4.41e-108: 336: 77.38
+	Hs
		1297131 TNR6C_HUMAN (35-1957): 8.26e-150: 513: 37.01		CNO6L_HUMAN (1-555): 3.57e-109: 338: 100.00
+	Hs
		1336211 TNR6C_HUMAN (35-1957): 8.26e-150: 513: 37.01		CNOT6_HUMAN (6-555): 4.41e-108: 336: 77.38
+	Dm
		1213159 GAWKY_DROME (718-1889): 1.06e-50: 200: 20.88		Q8IMX1_DROME (22-555): 5.44e-106: 331: 57.76
+	Hs
		998813 EP300_HUMAN (789-1765): 6.73e-09: 63.6: 9.05		PDE12_HUMAN (189-539): 4.41e-82: 270: 26.97
+	Hs
		1284131 RRBP1_HUMAN (329-778): 2.37e-09: 65.1: 13.30		LRC59_HUMAN (52-137): 1.03e-11: 68.2: 46.51