HitPredict

Interactor 1: TNR6A (Q8NDV7)
Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (EMSY interactor protein) (GW182 autoantigen) (Protein GW1) (Glycine-tryptophan protein of 182 kDa)
Gene: TNRC6A

Interactor 2: RC3H2 (Q9HBD1)
Roquin-2 (EC 2.3.2.27) (Membrane-associated nucleic acid-binding protein) (RING finger and CCCH-type zinc finger domain-containing protein 2) (RING finger protein 164) (RING-type E3 ubiquitin transferase Roquin-2)
Gene: RC3H2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29395067
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000932 - P-body GO:0003723 - RNA binding GO:0043231 - intracellular membrane-bounded organelle
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1962 Hs			1 1191
+	Hs
		1136182 TNR6A_HUMAN (1-1962): 0: 896: 100.00		RC3H1_HUMAN (1-1108): 0: 788: 49.30
+	Hs
		1335238 TNR6B_HUMAN (44-1944): 3.32e-153: 521: 33.57		RC3H2_HUMAN (1-1191): 0: 1105: 100.00
+	Hs
		1136358 TNR6B_HUMAN (44-1944): 3.32e-153: 521: 33.57		RC3H1_HUMAN (1-1108): 0: 788: 49.30
+	Hs
		1136304 TNR6C_HUMAN (35-1957): 8.26e-150: 513: 37.01		RC3H1_HUMAN (1-1108): 0: 788: 49.30
+	Hs
		1242603 TNR6A_HUMAN (1-1962): 0: 896: 100.00		KMT2C_HUMAN (351-895): 4.49e-14: 79.7: 9.35
+	Hs
		257662 TNR6A_HUMAN (1-1962): 0: 896: 100.00		ANR17_HUMAN (335-957): 1.44e-12: 74.7: 8.44
+	Hs
		1056895 TNR6A_HUMAN (1-1962): 0: 896: 100.00		MDC1_HUMAN (442-806): 1.14e-11: 71.8: 12.21
+	Hs
		325813 TNR6A_HUMAN (1-1962): 0: 896: 100.00		LATS1_HUMAN (518-1066): 1.1e-09: 65: 11.05
+	Hs
		257724 TNR6B_HUMAN (44-1944): 3.32e-153: 521: 33.57		ANR17_HUMAN (335-957): 1.44e-12: 74.7: 8.44
+	Hs
		257704 TNR6C_HUMAN (35-1957): 8.26e-150: 513: 37.01		ANR17_HUMAN (335-957): 1.44e-12: 74.7: 8.44
+	Hs
		325942 TNR6B_HUMAN (44-1944): 3.32e-153: 521: 33.57		LATS1_HUMAN (518-1066): 1.1e-09: 65: 11.05
+	Hs
		325899 TNR6C_HUMAN (35-1957): 8.26e-150: 513: 37.01		LATS1_HUMAN (518-1066): 1.1e-09: 65: 11.05
+	Hs
		554259 MUC1_HUMAN (845-1740): 1.98e-15: 84.9: 11.69		MUC1_HUMAN (344-901): 6.29e-21: 102: 9.70
+	Hs
		1056910 CBP_HUMAN (735-1745): 8.61e-21: 102: 9.54		MDC1_HUMAN (442-806): 1.14e-11: 71.8: 12.21
+	Hs
		1170076 CBP_HUMAN (735-1745): 8.61e-21: 102: 9.54		SRCAP_HUMAN (482-817): 8.67e-10: 65.7: 15.61
+	Hs
		325832 CBP_HUMAN (735-1745): 8.61e-21: 102: 9.54		LATS1_HUMAN (518-1066): 1.1e-09: 65: 11.05
+	Hs
		1270755 CBP_HUMAN (735-1745): 8.61e-21: 102: 9.54		CBP_HUMAN (556-893): 1.74e-09: 64.6: 9.77
+	Mm
		1351630 PCLO_MOUSE (19-1290): 1.41e-09: 66: 10.73		PCLO_MOUSE (522-1015): 6.21e-15: 82.8: 8.09
+	Hs
		1056898 ARI1B_HUMAN (551-1540): 1.58e-09: 65.5: 8.99		MDC1_HUMAN (442-806): 1.14e-11: 71.8: 12.21