HitPredict

Interactor 1: TNR6A (Q8NDV7)
Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (EMSY interactor protein) (GW182 autoantigen) (Protein GW1) (Glycine-tryptophan protein of 182 kDa)
Gene: TNRC6A

Interactor 2: CNOT2 (Q9NZN8)
CCR4-NOT transcription complex subunit 2 (CCR4-associated factor 2)
Gene: CNOT2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	29395067, 21981923
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000932 - P-body GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1962 Hs			1 540
+	Hs
		257384 TNR6A_HUMAN (1-1962): 0: 896: 100.00		CNOT3_HUMAN (4-524): 3.46e-106: 336: 16.19
+	Hs
		1349348 TNR6B_HUMAN (44-1944): 3.32e-153: 521: 33.57		CNOT2_HUMAN (1-540): 0: 528: 100.00
+	Hs
		1336203 TNR6C_HUMAN (35-1957): 8.26e-150: 513: 37.01		CNOT2_HUMAN (1-540): 0: 528: 100.00
+	Hs
		257428 TNR6B_HUMAN (44-1944): 3.32e-153: 521: 33.57		CNOT3_HUMAN (4-524): 3.46e-106: 336: 16.19
+	Hs
		257413 TNR6C_HUMAN (35-1957): 8.26e-150: 513: 37.01		CNOT3_HUMAN (4-524): 3.46e-106: 336: 16.19
+	Mm
		1206839 TNR6B_MOUSE (44-1944): 1.45e-146: 501: 31.87		CNOT3_MOUSE (4-524): 3.42e-109: 344: 17.14
+	Dm
		1249007 GAWKY_DROME (718-1889): 1.06e-50: 200: 20.88		RGA_DROME (22-534): 6.07e-96: 305: 29.50
+	Dm
		1178903 GAWKY_DROME (718-1889): 1.06e-50: 200: 20.88		Q7K126_DROME (4-525): 4.7e-76: 258: 15.41
+	Mm
		101458 F8VPR5_MOUSE (735-1757): 5.22e-19: 96.7: 10.60		CNOT3_MOUSE (4-524): 3.42e-109: 344: 17.14
+	Hs
		257347 EP300_HUMAN (789-1765): 6.73e-09: 63.6: 9.05		CNOT3_HUMAN (4-524): 3.46e-106: 336: 16.19
+	Dm
		113976 M9PB30_DROME (58-812): 9.58e-09: 63.2: 8.52		M9PB30_DROME (37-438): 2.6e-11: 69: 13.35