HitPredict

Interactor 1: TNR6A (Q8NDV7)
Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (EMSY interactor protein) (GW182 autoantigen) (Protein GW1) (Glycine-tryptophan protein of 182 kDa)
Gene: TNRC6A

Interactor 2: CNOT7 (Q9UIV1)
CCR4-NOT transcription complex subunit 7 (EC 3.1.13.4) (BTG1-binding factor 1) (CCR4-associated factor 1) (CAF-1) (Caf1a)
Gene: CNOT7

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.696

Property	Details
Experiments	29395067, 21984185, 21981923, 28813667
Identification Methods	proximity labelling technology, pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000932 - P-body GO:0003723 - RNA binding GO:0005829 - cytosol GO:0035195 - miRNA-mediated post-transcriptional gene silencing GO:0060213 - positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1962 Hs			1 285
+	Hs
		1242678 TNR6A_HUMAN (1-1962): 0: 896: 100.00		CNOT8_HUMAN (1-282): 6.3e-172: 478: 76.24
+	Hs
		1355898 TNR6B_HUMAN (44-1944): 3.32e-153: 521: 33.57		CNOT7_HUMAN (1-285): 0: 502: 100.00
+	Hs
		1336207 TNR6C_HUMAN (35-1957): 8.26e-150: 513: 37.01		CNOT7_HUMAN (1-285): 0: 502: 100.00
+	Hs
		1354674 TNR6B_HUMAN (44-1944): 3.32e-153: 521: 33.57		CNOT8_HUMAN (1-282): 6.3e-172: 478: 76.24
+	Hs
		1336204 TNR6C_HUMAN (35-1957): 8.26e-150: 513: 37.01		CNOT8_HUMAN (1-282): 6.3e-172: 478: 76.24
+	Dm
		90733 GAWKY_DROME (718-1889): 1.06e-50: 200: 20.88		E1JHY7_DROME (2-256): 6.53e-145: 412: 68.87