HitPredict

Interactor 1: TNR6A (Q8NDV7)
Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (EMSY interactor protein) (GW182 autoantigen) (Protein GW1) (Glycine-tryptophan protein of 182 kDa)
Gene: TNRC6A

Interactor 2: AGO2 (Q9UKV8)
Protein argonaute-2 (Argonaute2) (hAgo2) (EC 3.1.26.n2) (Argonaute RISC catalytic component 2) (Eukaryotic translation initiation factor 2C 2) (eIF-2C 2) (eIF2C 2) (PAZ Piwi domain protein) (PPD) (Protein slicer)
Gene: AGO2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 0.60 0.762

The method score is based on:

Property Details
Experiments 28813667, 29395067, 34518544, 35271311, 19470757, 19383768, 19716330, 24778252, 17938239, 22484317, 28877994, 28683311, 19324964, 21840310, 23090477
Identification Methods affinity chromatography technology, proximity labelling technology, pull down, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000932 - P-body
GO:0003723 - RNA binding
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0016442 - RISC complex
and 2 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024