HitPredict

Interactor 1: GPR31 (O00270)
12-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid receptor (12-(S)-HETE receptor) (12-HETER) (G-protein coupled receptor 31) (GPR31/12-HETER)
Gene: GPR31

Interactor 2: RASN (P01111)
GTPase NRas (EC 3.6.5.2) (Transforming protein N-Ras)
Gene: NRAS

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	28619714
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 319 Hs			1 189
+	Hs
		124272 GPR31_HUMAN (1-319): 6.29e-103: 305: 100.00		RASK_HUMAN (16-189): 7.56e-85: 249: 85.71
+	Hs
		124271 GPR31_HUMAN (1-319): 6.29e-103: 305: 100.00		RASH_HUMAN (1-188): 8.6e-78: 232: 85.64
+	Hs
		350150 MTR1L_HUMAN (1-303): 4.74e-63: 212: 18.89		RASK_HUMAN (16-189): 7.56e-85: 249: 85.71
+	Hs
		348541 ADA1B_HUMAN (7-301): 2.03e-65: 215: 19.94		RASN_HUMAN (1-189): 9.9e-80: 236: 100.00
+	Hs
		348650 MTR1L_HUMAN (1-303): 4.74e-63: 212: 18.89		RASN_HUMAN (1-189): 9.9e-80: 236: 100.00
+	Hs
		428999 ADRB2_HUMAN (2-306): 5.63e-69: 222: 18.94		RAB14_HUMAN (4-185): 2.1e-73: 221: 29.35
+	Hs
		506375 CXCR4_HUMAN (15-300): 1.04e-83: 258: 21.99		RALA_HUMAN (4-169): 7.15e-59: 184: 53.89
+	Hs
		349150 CCR1_HUMAN (9-300): 5.77e-61: 199: 24.92		RASH_HUMAN (1-188): 8.6e-78: 232: 85.64
+	Hs
		674840 AGTR1_HUMAN (10-308): 1.07e-63: 207: 21.31		RB11A_HUMAN (4-184): 1.5e-74: 224: 33.88
+	Hs
		686630 CCR1_HUMAN (9-300): 5.77e-61: 199: 24.92		RAB14_HUMAN (4-185): 2.1e-73: 221: 29.35
+	Mm
		677228 SSR3_MOUSE (15-317): 1.28e-65: 213: 23.66		RAP1A_MOUSE (1-165): 1.22e-60: 188: 56.29
+	Mm
		677236 SSR3_MOUSE (15-317): 1.28e-65: 213: 23.66		RALA_MOUSE (4-169): 1.3e-58: 184: 53.89
+	Hs
		666303 NK3R_HUMAN (4-300): 9.14e-62: 205: 20.59		RAP1A_HUMAN (1-165): 1.22e-60: 188: 56.29
+	Mm
		677462 SSR3_MOUSE (15-317): 1.28e-65: 213: 23.66		RALB_MOUSE (4-170): 1.95e-55: 176: 52.07
+	Hs
		63221 CCR1_HUMAN (9-300): 5.77e-61: 199: 24.92		RP1BL_HUMAN (1-165): 6.97e-60: 186: 55.69