Interactor 1: DFFA (O00273)
DNA fragmentation factor subunit alpha (DNA fragmentation factor 45 kDa subunit) (DFF-45) (Inhibitor of CAD) (ICAD)
Gene: DFFA

Interactor 2: DFFB (O76075)
DNA fragmentation factor subunit beta (EC 3.-.-.-) (Caspase-activated deoxyribonuclease) (CAD) (Caspase-activated DNase) (Caspase-activated nuclease) (CPAN) (DNA fragmentation factor 40 kDa subunit) (DFF-40)
Gene: DFFB

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.974

The method score is based on:

Property Details
Experiments 26186194, 28514442, 17353931, 32296183, 10527860, 33961781, unassigned1304, 11371636, 19882353, 9108473
Identification Methods affinity chromatography technology, two hybrid, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, validated two hybrid, nuclear magnetic resonance, two hybrid array, two hybrid prey pooling approach, coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains CIDE-N~CIDE-N
Common GO terms GO:0000785 - chromatin
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0006309 - apoptotic DNA fragmentation
and 3 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 331
Hs

1 338
+ Mm
+ Hs
+ Dm
+ Dm
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024