HitPredict

Interactor 1: MCU (Q8NE86)
Calcium uniporter protein, mitochondrial (HsMCU) (Coiled-coil domain-containing protein 109A)
Gene: MCU

Interactor 2: MCU (Q8NE86)
Calcium uniporter protein, mitochondrial (HsMCU) (Coiled-coil domain-containing protein 109A)
Gene: MCU

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.69 1.00 0.834

The method score is based on:

Property Details
Experiments 30638448, 21685886, 29995857
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, cross-linking study
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains MCU~MCU
Common GO terms GO:0005262 - calcium channel activity
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0006851 - mitochondrial calcium ion transmembrane transport
GO:0015292 - uniporter activity
and 11 others

more...
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 351
Hs

1 351
+ Mm
+ Dr
+ Hs
+ Mm
+ Ce
+ Nc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024