HitPredict

Interactor 1: MCU (Q8NE86)
Calcium uniporter protein, mitochondrial (HsMCU) (Coiled-coil domain-containing protein 109A)
Gene: MCU

Interactor 2: EMRE (Q9H4I9)
Essential MCU regulator, mitochondrial (Single-pass membrane protein with aspartate-rich tail 1, mitochondrial)
Gene: SMDT1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.72 0.90 0.809

The method score is based on:

Property Details
Experiments 27173435, 33961781, 32494073
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains DDDD~MCU
Common GO terms GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0006851 - mitochondrial calcium ion transmembrane transport
GO:0036444 - calcium import into the mitochondrion
GO:0051560 - mitochondrial calcium ion homeostasis
and 1 others

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Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024