Interactor 1: MCU (Q8NE86)
Calcium uniporter protein, mitochondrial (HsMCU) (Coiled-coil domain-containing protein 109A)
Gene: MCU

Interactor 2: MCUB (Q9NWR8)
Calcium uniporter regulatory subunit MCUb, mitochondrial (MCUb) (Coiled-coil domain-containing protein 109B)
Gene: MCUB

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 32877691
Identification Methods proximity labelling technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains MCU~MCU
Common GO terms GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0006851 - mitochondrial calcium ion transmembrane transport
GO:0034704 - calcium channel complex
GO:0036444 - calcium import into the mitochondrion
and 2 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 351
Hs

1 336
+ Mm
+ Hs
+ Mm
+ Dr
+ Ce
+ Nc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024