HitPredict

Interactor 1: RFXAP (O00287)
Regulatory factor X-associated protein (RFX-associated protein) (RFX DNA-binding complex 36 kDa subunit)
Gene: RFXAP

Interactor 2: RFXK (O14593)
DNA-binding protein RFXANK (Ankyrin repeat family A protein 1) (Regulatory factor X subunit B) (RFX-B) (Regulatory factor X-associated ankyrin-containing protein)
Gene: RFXANK

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.88	0.60	0.729

The method score is based on:

Property	Details
Experiments	25752541, 11463838, 33961781, 10825209, 10938133
Identification Methods	affinity chromatography technology, pull down, two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II GO:0045348 - positive regulation of MHC class II biosynthetic process GO:0045944 - positive regulation of transcription by RNA polymerase II and 1 others more... GO:0090575 - RNA polymerase II transcription regulator complex
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1	272
Hs

1	260

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024