Interactor 1: RFXAP (O00287)
Regulatory factor X-associated protein (RFX-associated protein) (RFX DNA-binding complex 36 kDa subunit)
Gene: RFXAP

Interactor 2: RFX5 (P48382)
DNA-binding protein RFX5 (Regulatory factor X 5)
Gene: RFX5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.90 0.90 0.905

The method score is based on:

Property Details
Experiments 9118943, 26496610, 28514442, 33961781, 20732328, 10938133
Identification Methods two hybrid, affinity chromatography technology, solution state nmr, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, pull down
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains RFX5_N~RFXA_RFXANK_bdg
Common GO terms GO:0005634 - nucleus
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0045348 - positive regulation of MHC class II biosynthetic process
GO:0045944 - positive regulation of transcription by RNA polymerase II
GO:0090575 - RNA polymerase II transcription regulator complex
Homologous interactions 0

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Last updated: 15 Jul 2024