HitPredict

Interactor 1: INT5 (Q6P9B9)
Integrator complex subunit 5 (Int5)
Gene: INTS5

Interactor 2: INT1 (Q8N201)
Integrator complex subunit 1 (Int1)
Gene: INTS1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

The method score is based on:

Property	Details
Experiments	20133760, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	INTS1_R4~INTS5_C
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016020 - membrane GO:0016180 - snRNA processing GO:0031965 - nuclear membrane and 4 others more... GO:0032039 - integrator complex GO:0034243 - regulation of transcription elongation by RNA polymerase II GO:0160232 - INTAC complex GO:0160240 - RNA polymerase II transcription initiation surveillance
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1	1019
Hs

1	2190

Service provided by Combinatics, Japan

Last updated: 11Aug2025