Interactor 1: HIP1 (O00291)
Huntingtin-interacting protein 1 (HIP-1) (Huntingtin-interacting protein I) (HIP-I)
Gene: HIP1

Interactor 2: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 35256949
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains ANTH~ubiquitin
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005794 - Golgi apparatus
GO:0005829 - cytosol
GO:0042981 - regulation of apoptotic process
and 2 others

more...

Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 1037
Hs

1 465
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024