HitPredict

Interactor 1: HIP1 (O00291)
Huntingtin-interacting protein 1 (HIP-1) (Huntingtin-interacting protein I) (HIP-I)
Gene: HIP1

Interactor 2: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	26269332, 35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0006919 - activation of cysteine-type endopeptidase activity involved in apoptotic process GO:0035091 - phosphatidylinositol binding
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1037 Hs			1 758
+	Hs
		497870 TLN1_HUMAN (191-1020): 2.49e-92: 326: 17.91		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		497875 TLN2_HUMAN (194-1021): 5.62e-76: 276: 16.84		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		496438 MYH9_HUMAN (103-1037): 7.13e-48: 189: 8.73		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		497769 MYH2_HUMAN (216-1036): 1.36e-35: 149: 8.84		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		496439 MYH10_HUMAN (26-829): 1.87e-29: 129: 10.64		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Rn
		582036 MYH10_RAT (286-1037): 1.81e-35: 149: 9.09		TAU_RAT (1-758): 4.86e-75: 260: 71.47
+	Rn
		94262 MYH10_RAT (286-1037): 1.81e-35: 149: 9.09		F1LST4_RAT (1-757): 8.59e-75: 260: 71.56
+	Hs
		64577 MYH7B_HUMAN (372-680): 7.35e-12: 72.2: 23.31		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Dm
		1370280 Q9VSL8_DROME (614-1023): 3.42e-62: 234: 22.70		Q9VLS7_DROME (62-753): 1.93e-12: 73.2: 9.96