HitPredict

Interactor 1: HIP1 (O00291)
Huntingtin-interacting protein 1 (HIP-1) (Huntingtin-interacting protein I) (HIP-I)
Gene: HIP1

Interactor 2: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31324722
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 1037 Hs			1 1480
+	Hs
		529956 TLN1_HUMAN (191-1020): 2.49e-92: 326: 17.91		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		528675 MYH9_HUMAN (103-1037): 7.13e-48: 189: 8.73		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		529895 MYH2_HUMAN (216-1036): 1.36e-35: 149: 8.84		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		522533 MYH1_HUMAN (338-1037): 5.28e-33: 141: 9.75		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		528682 MYH11_HUMAN (32-821): 2.76e-32: 138: 11.60		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		528400 MYH8_HUMAN (366-1037): 1.09e-31: 136: 10.03		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		528676 MYH10_HUMAN (26-829): 1.87e-29: 129: 10.64		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		522586 MYH7_HUMAN (38-671): 6.11e-21: 101: 10.80		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		529968 MRCKB_HUMAN (514-1037): 7.32e-18: 91.6: 13.43		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		529972 MYH4_HUMAN (24-574): 1.01e-14: 81.3: 9.01		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		502902 MYH3_HUMAN (24-568): 1.5e-14: 81: 9.34		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		529896 MYH13_HUMAN (17-565): 1.77e-14: 80.6: 9.73		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		528357 MYH6_HUMAN (38-499): 4.52e-12: 72.9: 10.37		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		64579 MYH7B_HUMAN (372-680): 7.35e-12: 72.2: 23.31		CFTR_HUMAN (1-1480): 0: 1031: 100.00