Interactor 1: HIP1 (O00291)
Huntingtin-interacting protein 1 (HIP-1) (Huntingtin-interacting protein I) (HIP-I)
Gene: HIP1

Interactor 2: HD (P42858)
Huntingtin (Huntington disease protein) (HD protein) [Cleaved into: Huntingtin, myristoylated N-terminal fragment]
Gene: HTT

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 0.60 0.749

The method score is based on:

Property Details
Experiments 11063258, 15383276, 9140394, 9147654, 32814053, 22835334, 17500595
Identification Methods two hybrid, pull down, affinity chromatography technology, validated two hybrid, anti tag coimmunoprecipitation, two hybrid array, two hybrid pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005794 - Golgi apparatus
GO:0005829 - cytosol
GO:0006915 - apoptotic process
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 1037
Hs

1 3142
+ Mm
+ Mm
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024