Interactor 1: VP37A (Q8NEZ2)
Vacuolar protein sorting-associated protein 37A (hVps37A) (ESCRT-I complex subunit VPS37A) (Hepatocellular carcinoma-related protein 1)
Gene: VPS37A

Interactor 2: TS101 (Q99816)
Tumor susceptibility gene 101 protein (ESCRT-I complex subunit TSG101)
Gene: TSG101

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.983

The method score is based on:

Property Details
Experiments 21757351, 15240819, 33961781, 25416956, 15604093, 27609421, 15218037, 32296183, 31519728, 35271311, 22405001, 24284069, unassigned1304
Identification Methods affinity chromatography technology, two hybrid, pull down, two hybrid prey pooling approach, two hybrid array, mammalian protein protein interaction trap, anti tag coimmunoprecipitation, validated two hybrid
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Mod_r~Vps23_core
Common GO terms GO:0000813 - ESCRT I complex
GO:0005813 - centrosome
GO:0005829 - cytosol
GO:0010008 - endosome membrane
GO:0016236 - macroautophagy
and 6 others

more...

Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 397
Hs

1 390
+ Hs
+ Hs
+ Dm
+ Hs
+ Dm
+ Ce
+ At
+ At
+ At
+ Dm
+ Dm

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Last updated: 15 Jul 2024